Sinonasal NK/T-cell lymphoma
نویسندگان
چکیده
منابع مشابه
NKT Cell Responses to B Cell Lymphoma
Natural killer T (NKT) cells are a unique subset of CD1d-restricted T lymphocytes that express characteristics of both T cells and natural killer cells. NKT cells mediate tumor immune-surveillance; however, NKT cells are numerically reduced and functionally impaired in lymphoma patients. Many hematologic malignancies express CD1d molecules and co-stimulatory proteins needed to induce anti-tumor...
متن کامل[A case of sinonasal lymphoma].
Sinonasal lymphoma is a rare disease that poses difficulties in diagnosis. A fifty-year-old male patient presented with a mass in the nasal vestibulum that destroyed the left nasal ala. Nocardiosis was considered in the light of the initial biopsy findings; however, microbiologic studies were not consistent with pathologic examination. A subsequent biopsy was obtained, which resulted in the dia...
متن کاملSinonasal lymphoma: a case report.
Sinonasal lymphomas are uncommon malignancies. They are difficult to differentiate from carcinomas, and immunohistochemistry is needed to make the diagnosis. We describe an unusual case of a T cell lymphoma that involved only the paranasal sinuses in a middle-aged man. The patient presented with a complete loss of vision in one eye and lateral rectus muscle palsy, but no nasal symptoms.
متن کاملNKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.
Immunomodulators are effective in controlling hematologic malignancy by initiating or reactivating host antitumor immunity to otherwise poorly immunogenic and immune suppressive cancers. We aimed to boost antitumor immunity in B-cell lymphoma by developing a tumor cell vaccine incorporating α-galactosylceramide (α-GalCer) that targets the immune adjuvant properties of NKT cells. In the Eμ-myc t...
متن کاملSpecific c-kit mutations in sinonasal natural killer/T-cell lymphoma in China and Japan.
Sinonasal lymphoma is one of the constituents of lethal midline granuloma, which is a clinical term for progressive, destructive lesions affecting the midline of the face. The majority of sinonasal lymphomas, especially those showing polymorphous patterns of proliferation and thus termed polymorphic reticulosis, recently were categorized as sinonasal natural killer/T-cell lymphomas. They are mo...
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ژورنال
عنوان ژورنال: European Annals of Otorhinolaryngology, Head and Neck Diseases
سال: 2013
ISSN: 1879-7296
DOI: 10.1016/j.anorl.2012.01.005